Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717203 | 0.93 | DRD2 (0.43) | DRD4DRD2CHRM4ALDH1A1POLB | |
| SCHEMBL7716779 | 0.83 | CHRM4 (0.47) | CHRM4DPP4DPP8DPP9MTOR | |
| SCHEMBL31042542 | 0.82 | DRD4 (0.45) | DRD4DRD2CHRM4ALDH1A1POLB | |
| SCHEMBL7711167 | 0.82 | NPC1 (0.56) | ALDH1A1MAPTKDM4EPDCD1CD274 | |
| SCHEMBL7714987 | 0.80 | KDM4E (0.44) | DRD4DRD2CHRM4ALDH1A1GRM5 | |
| SCHEMBL31042529 | 0.80 | CHRM4 (0.50) | DRD4DRD2CHRM4ALDH1A1POLB | |
| SCHEMBL20149778 | 0.80 | DRD4 (0.43) | DRD4DRD2CHRM4ALDH1A1GRM5 | |
| SCHEMBL8003101 | 0.79 | DRD4 (0.42) | DRD4GAAKDM4E | |
| SCHEMBL31042527 | 0.79 | DRD4 (0.51) | DRD4DRD2CHRM4ALDH1A1POLB | |
| SCHEMBL7715013 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4EPDCD1CD274CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |