Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715017 | 0.85 | HRH1 (0.43) | KDM4EMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7711167 | 0.81 | NPC1 (0.56) | KDM4EMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7715922 | 0.79 | DRD4 (0.47) | KDM4EMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7718924 | 0.78 | TSHR (0.51) | — | |
| SCHEMBL7719028 | 0.77 | MYC (0.44) | KDM4EMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7718948 | 0.77 | NPY1R (0.49) | KDM4EMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2553609 | 0.75 | CKS1B (0.54) | KMT2AHRH1CCR3KCNH2KDM1A | |
| SCHEMBL8683997 | 0.75 | FABP3 (0.55) | KDM4EMEN1KMT2ANPSR1HRH1 | |
| SCHEMBL8005392 | 0.74 | HRH1 (0.41) | KDM4EMEN1KMT2AHRH1CCR3 | |
| SCHEMBL2555150 | 0.74 | NOTUM (0.55) | KDM4EMEN1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |