⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630769 | 1.00 | — | — | |
| SCHEMBL8102643 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL17651927 | 0.71 | MAP3K14 (0.36) | — | |
| SCHEMBL8767797 | 0.68 | ITGB1 (0.38) | — | |
| SCHEMBL8094790 | 0.68 | — | — | |
| SCHEMBL6687753 | 0.67 | — | — | |
| SCHEMBL11100807 | 0.67 | — | — | |
| SCHEMBL9406800 | 0.67 | — | — | |
| SCHEMBL10464804 | 0.67 | — | — | |
| SCHEMBL8110089 | 0.65 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002363155-A | METHOD FOR PRODUCING 4-ACYLOXY-2-AZETIDINONE DERIVATIVE | KANEGAFUCHI CHEM IND CO LTD | 2002-12-18 | — | — | JP | disclosed |
| US-5075439-A | Processes for (3S,4R)-3-[1(R)-t-butyl-dimethylsilyloxy)-ethyl]-4-[1-oxo-3-thiolanylthio(thiocarbonyl)thio]azetidin-2-ones and intermediates therefor | PFIZER INC. (US) | 1991-12-24 | — | — | US | disclosed |
| US-4772692-A | AZETIDINONES | HOECHST UK LIMITED (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0069377-B1 | ANTIBACTERIAL PENEM DERIVATIVES | HOECHST UK LIMITED (GB) | 1988-06-22 | — | — | EP | disclosed |
| US-4684640-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-04 | — | — | US | disclosed |
| EP-0091576-B1 | 7-OXO-4-THIA-1-AZABICYCLO(3,2,0)HEPTANE DERIVATIVES | HOECHST UK LIMITED (GB) | 1987-07-29 | — | — | EP | disclosed |
| US-4639441-A | ANTIBACTERIAL PENICILLINS | SANKYO COMPANY LIMITED (JP) | 1987-01-27 | — | — | US | disclosed |
| EP-0069378-B1 | ANTIBACTERIAL PENEM DERIVATIVES | HOECHST UK LIMITED (GB) | 1987-01-07 | — | — | EP | disclosed |
| EP-0051813-B1 | 7-OXO-4-THIA-1-AZA(3,2,0)HEPTANE AND 7-OXO-4-THIA-1-AZA(3,2,0)HEPT-2-ENE DERIVATIVES | HOECHST UK LIMITED (GB) | 1986-07-30 | — | — | EP | disclosed |
| EP-0185651-A1 | Intermediates for the production of antibacterial penem derivates | HOECHST UK LIMITED (GB) | 1986-06-25 | — | — | EP | disclosed |
| US-4585767-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0176064-A1 | Intermediates for the production of 7-oxo-4-thia-1-aza[3,2,0]heptane and 7-oxo-4-thia-1-aza[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-04-02 | — | — | EP | disclosed |
| US-4526718-A | 3,3-Di(acylthio)-2(4-allylthioazetidin-2-on-1-yl)propenoic acid ester compounds | HOECHST UK LIMITED (GB) | 1985-07-02 | — | — | US | disclosed |
| US-4510086-A | 2(4-Allylthioazetidin-2-on-1-yl)acetic acid ester compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-09 | — | — | US | disclosed |
| US-4474793-A | 7-Oxo-4-thia-1-aza[3,2,0]heptane and 7-oxo-4-thia-1-aza[3,2,0]hept-2-ene derivatives | HOECHST U.K. LIMITED (GB) | 1984-10-02 | — | — | US | disclosed |
| EP-0069377-A2 | Antibacterial penem derivatives | HOECHST UK LIMITED (GB) | 1983-01-12 | — | — | EP | disclosed |
| EP-0069378-A2 | Antibacterial penem derivatives | HOECHST UK LIMITED (GB) | 1983-01-12 | — | — | EP | disclosed |
| EP-0051813-A2 | 7-Oxo-4-thia-1-aza(3,2,0)heptane and 7-oxo-4-thia-1-aza(3,2,0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1982-05-19 | — | — | EP | disclosed |