Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202966 | 0.85 | CTSK (0.53) | DPP4CTSKDRD2KDM4DGPR119 | |
| SCHEMBL13245164 | 0.85 | PRKAA2 (0.53) | CHRM4PRKAA2 | |
| SCHEMBL7013614 | 0.83 | ITGB3 (0.49) | DRD2KDM4DEPHX1GPR119 | |
| SCHEMBL7711219 | 0.83 | DRD2 (0.48) | CHRM4DRD2EPHX1KCNA3 | |
| SCHEMBL8665014 | 0.81 | CTSK (0.57) | CTSKDRD2KDM4DKCNA3 | |
| SCHEMBL7715921 | 0.80 | FFAR4 (0.40) | CHRM4CTSKDRD2EPHX1KCNA3 | |
| SCHEMBL7714679 | 0.79 | CHRM4 (0.49) | DPP4CHRM4DRD2KDM4DKCNA3 | |
| SCHEMBL7711061 | 0.78 | CHRM4 (0.48) | DPP4CHRM4KCNA3 | |
| SCHEMBL7716756 | 0.76 | DRD2 (0.51) | DRD2EPHX1CHRM2 | |
| SCHEMBL5619433 | 0.75 | EPHX1 (0.60) | CTSKDRD2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |