Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359766 | 0.86 | MAPT (0.53) | HDAC2HDAC8AKR1B10AKR1B1RELA | |
| SCHEMBL8359765 | 0.86 | MAPT (0.53) | HDAC2HDAC8AKR1B10AKR1B1RELA | |
| SCHEMBL30665840 | 0.83 | AKR1B10 (0.52) | AKR1B10AKR1B1MMP1MMP2MMP9 | |
| SCHEMBL414597 | 0.77 | HDAC2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC2 | |
| SCHEMBL30584137 | 0.77 | HDAC2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC2 | |
| SCHEMBL414598 | 0.77 | HDAC2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC2 | |
| SCHEMBL6732593 | 0.77 | NR1H4 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC2 | |
| SCHEMBL6729973 | 0.77 | TTR (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4AKR1B10 | |
| SCHEMBL6732590 | 0.77 | NR1H4 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC2 | |
| SCHEMBL6729975 | 0.77 | TTR (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6373618-B1 | Chromogenic glazing for automobiles and display filters | SCHOTT-DONNELLY, LLC | 2002-04-16 | — | — | US | disclosed |