Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359765 | 1.00 | MAPT (0.53) | MAPTLMNAALDH1A1HDAC3HDAC4 | |
| SCHEMBL7716080 | 0.86 | PLAAT3 (0.46) | MAPTLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL2547176 | 0.84 | CA12 (0.61) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL1299521 | 0.84 | CA12 (0.61) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL2482797 | 0.83 | MAPT (0.55) | MAPTLMNAALDH1A1HDAC3HDAC4 | |
| SCHEMBL2482799 | 0.83 | MAPT (0.55) | MAPTLMNAALDH1A1HDAC3HDAC4 | |
| SCHEMBL30665840 | 0.83 | AKR1B10 (0.52) | AKR1B10AKR1B1MAOBMMP1MMP2 | |
| SCHEMBL28642663 | 0.82 | KMT2A (0.49) | MAPTLMNAALDH1A1HDAC3HDAC4 | |
| SCHEMBL10351500 | 0.81 | MAPT (0.53) | MAPTLMNAALDH1A1HDAC3HDAC4 | |
| SCHEMBL10351502 | 0.81 | MAPT (0.53) | MAPTLMNAALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12360455-B2 | Poly(cyanocinnamate)s for structural and optical applications | BREWER SCIENCE, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| CN-115677536-A | Synthetic method and application of cyantraniliprole and derivatives thereof | 南京农业大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-114729001-A | Oleane phenylpropenamide derivative and preparation method and application thereof | 鲁南制药集团股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113698417-B | Spiro compound and preparation method and application thereof | 上海凯毕淬化学科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-113845443-A | Preparation method and intermediate of 2-cyano-3-amino acrylate compound | 江苏省农药研究所股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113698417-A | Spiro compound and preparation method and application thereof | 上海凯毕淬化学科技有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113402424-A | Synthetic method of cyanoacrylate compound | 上海泰初化工技术有限公司 | 2021-09-17 | — | — | CN | disclosed |
| US-9505733-B2 | Single step enantioselective process for the preparation of 3-substituted chiral phthalides | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-29 | — | — | US | disclosed |
| EP-2934147-A1 | COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND | BASF Agro B.V. (NL) | 2015-10-28 | — | — | EP | disclosed |
| US-20150299154-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-10-22 | — | — | US | disclosed |
| US-9073887-B2 | Single step enantioselective process for the preparation of 3-substituted chiral phthalides | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140330027-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-11-06 | — | — | US | disclosed |
| WO-2014095994-A1 | COMPOSITIONS COMPRISING A TRIAZOLE COMPOUND | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014086851-A1 | COMPOSITIONS COMPRISING A QUILLAY EXTRACT AND A FUNGICIDAL INHIBITOR OF RESPIRATORY COMPLEX III AT QO SITE | BASF AGRO B.V., ARNHEM (NL) (CH) | 2014-06-12 | — | — | WO | disclosed |
| WO-2013072830-A9 | A SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-20 | — | — | WO | disclosed |
| WO-2013072830-A1 | A SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | WO | disclosed |
| CN-101417962-B | Method for preparing 2-cyano-3-amino acrylic ester derivates | JIANGSU PESTICIDE RES INST CO LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-101417962-A | Method for preparing 2-cyano-3-amino acrylic ester derivates | JIANGSU PESTICIDE RES INST CO (CN) | 2009-04-29 | — | — | CN | disclosed |
| WO-1999036049-A1 | PHOTOSTABLE UV ABSORBENT CONTAINING α-CYANO CINNAMYL MOIETY | ISP INVESTMENTS INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| US-5830441-A | SUNSCREEN AGENTS | ISP INVESTMENTS INC. (US) | 1998-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330027-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | PPOX, NFE2L2, CBR1 | MAPT 2273/4885LMNA 2962/4885ALDH1A1 406/4885 |
| US-20150299154-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | PPOX, NFE2L2, CBR1 | MAPT 2273/4885LMNA 2962/4885ALDH1A1 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.