Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | UBE2I | P63279 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767200 | 0.82 | IDO1 (0.51) | NPSR1MAPTIDO1ALDH1A1 | |
| SCHEMBL1444265 | 0.78 | ALDH1A1 (0.48) | NPSR1MAPTALDH1A1MAPK1HPGD | |
| SCHEMBL2565533 | 0.77 | KMT2A (0.40) | MAPTHTTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6314235 | 0.76 | LMNA (0.54) | HTTIDO1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL6667630 | 0.76 | IDO1 (0.55) | MAPTHTTIDO1L3MBTL1ALDH1A1 | |
| SCHEMBL20724254 | 0.74 | IDO1 (0.53) | MAPTHTTIDO1L3MBTL1ALDH1A1 | |
| SCHEMBL8589633 | 0.73 | IDO1 (0.51) | NPSR1MAPTHTTIDO1L3MBTL1 | |
| SCHEMBL22793199 | 0.72 | TDP1 (0.57) | TDP1MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL286684 | 0.72 | IDO1 (0.58) | NPSR1MAPTHTTIDO1L3MBTL1 | |
| SCHEMBL11317760 | 0.72 | MTNR1A (0.53) | NPSR1MAPTHTTIDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | claimed |