Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823569 | 0.88 | ALDH1A1 (0.40) | NPC1RAB9AMAPTALDH1A1MAPK1 | |
| SCHEMBL8653487 | 0.87 | GPR84 (0.35) | GPR84NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6919860 | 0.84 | PARP1 (0.38) | GPR84MAPTALDH1A1MAPK1GSK3B | |
| SCHEMBL7303318 | 0.80 | NPSR1 (0.41) | GPR84NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL27334926 | 0.80 | GPR84 (0.41) | GPR84NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7718459 | 0.79 | ALDH1A1 (0.42) | MAPTALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL6551226 | 0.78 | TSHR (0.34) | GPR84NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9873189 | 0.78 | GPR84 (0.37) | GPR84NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL833 | 0.78 | GPR84 (0.37) | GPR84NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL27542325 | 0.78 | GPR84 (0.37) | GPR84NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407258-B1 | CYCLIZATION A AMINOAMIDE COMPOUND IN PRESENCE OF ANALKYLPHOSPHONIC ANHYDRIDE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-18 | — | — | US | disclosed |