Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.44 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.44 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 6/20 | 0.38 |
| ▸ | CDC25B | P30305 | 4/20 | 0.38 |
| ▸ | TDP2 | O95551 | 5/20 | 0.36 |
| ▸ | G6PD | P11413 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 4/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720787 | 0.91 | S100A4 (0.44) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL7721595 | 0.82 | PADI1 (0.50) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL7721606 | 0.74 | S100A4 (0.47) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL7721587 | 0.72 | S100A4 (0.50) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL6692403 | 0.66 | CHKA (0.46) | GAA | |
| SCHEMBL21801777 | 0.65 | PADI1 (0.64) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL7651620 | 0.65 | PADI1 (0.58) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL6688709 | 0.65 | BACE1 (0.60) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL7721594 | 0.64 | PADI1 (0.50) | PADI1PADI3PADI4PADI2TGM2 | |
| SCHEMBL851567 | 0.64 | CHKA (0.50) | TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391064-B1 | DYEING HAIR WITH AMINE QUINOLONE DERIVATIVES | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | disclosed |
| EP-0984010-B1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | OREAL (FR) | 2001-06-20 | — | — | EP | disclosed |
| EP-0984010-A1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |