Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 5/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.42 |
| ▸ | RXRG | P48443 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765770 | 0.91 | CES2 (0.47) | LMNARXRARXRBRXRGCES2 | |
| SCHEMBL28327548 | 0.83 | KDM4E (0.54) | LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL9492308 | 0.82 | KIF11 (0.53) | LMNACES2ALDH1A1MAPT | |
| SCHEMBL15763985 | 0.81 | MAPT (0.44) | LMNARXRARXRBRXRGCES2 | |
| SCHEMBL2191360 | 0.80 | ESR1 (0.44) | LMNARXRARXRBRXRGCES2 | |
| SCHEMBL29000619 | 0.80 | CES2 (0.44) | LMNARXRARXRBRXRGCES2 | |
| SCHEMBL7647561 | 0.79 | CES2 (0.50) | LMNARXRARXRBRXRGCES2 | |
| Butane SCHEMBL1043809 | 0.79 | FAAH (0.53) | LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL12758761 | 0.77 | CES2 (0.41) | LMNARXRARXRBRXRGCES2 | |
| SCHEMBL1996035 | 0.77 | BCL9 (0.44) | LMNARXRARXRBRXRGCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731070-A | Asymmetric catalytic synthesis method and application of chiral secondary phosphorus oxide and chiral aza-arene substituted tertiary phosphorus oxide | 河南工业大学 | 2023-09-12 | — | — | CN | disclosed |
| US-6395921-B1 | DEPROTINATION, COPPER SALT AND DILUENTS, HYDROLYSIS AND DECARBOXYLATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |