Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304399 | 0.79 | TYR (0.40) | ALDH1A1KMT2A | |
| SCHEMBL6133199 | 0.72 | TTR (0.33) | ALDH1A1 | |
| SCHEMBL1620760 | 0.70 | ERN1 (0.33) | ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL4120625 | 0.69 | LMNA (0.34) | ALDH1A1TRIM24TRIM33MEN1HPGD | |
| SCHEMBL8149465 | 0.69 | ADRB1 (0.41) | TSHR | |
| SCHEMBL10349585 | 0.69 | ALDH1A1 (0.39) | ALDH1A1PTGS2MEN1MAPTHPGD | |
| SCHEMBL9342327 | 0.69 | L3MBTL1 (0.41) | ALDH1A1SRD5A2MEN1MAPTHPGD | |
| SCHEMBL1175972 | 0.68 | UNG (0.47) | UNGALDH1A1TRIM24TRIM33PTGS2 | |
| SCHEMBL7617910 | 0.68 | ALDH1A1 (0.40) | ALDH1A1PTGS2MEN1MAPTHPGD | |
| SCHEMBL9347230 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369226-B1 | ENZYME INHIBITORS | AGOURON PHARMACEUTICALS, INC. | 2002-04-09 | — | — | US | disclosed |