Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717756 | 0.91 | GRIN2B (0.41) | LMNAGRIN2BMEN1KMT2AGRIN1 | |
| SCHEMBL22815269 | 0.71 | KDM1A (0.48) | KDM1ALMNAHSD17B10ESR1ESR2 | |
| SCHEMBL7717290 | 0.71 | LMNA (0.39) | KDM1ALMNAHSD17B10ESR1ESR2 | |
| SCHEMBL7717293 | 0.71 | LMNA (0.39) | KDM1ALMNAHSD17B10ESR1ESR2 | |
| SCHEMBL20017320 | 0.70 | KDM1A (0.54) | KDM1ALMNAHSD17B10ESR1ESR2 | |
| SCHEMBL27608796 | 0.67 | HTR2A (0.41) | LMNACYP2C19HTR2ATAAR1 | |
| SCHEMBL15155598 | 0.66 | CYP2C19 (0.52) | LMNAHSD17B10ESR1IDO1TDO2 | |
| SCHEMBL18891357 | 0.65 | KMT2A (0.48) | HSD17B10ESR1GRIN2BMEN1KMT2A | |
| SCHEMBL7717284 | 0.65 | GRIN2D (0.61) | KDM1ALMNAHSD17B10ALDH1A1GRIN2B | |
| SCHEMBL7717283 | 0.65 | GRIN2D (0.61) | KDM1ALMNAHSD17B10ALDH1A1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |