Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717293 | 1.00 | LMNA (0.39) | LMNAHSD17B10ESR1ESR2MEN1 | |
| SCHEMBL7717758 | 0.90 | MEN1 (0.41) | LMNAMEN1KMT2ANOS2CYP2D6 | |
| SCHEMBL7717755 | 0.90 | MEN1 (0.41) | LMNAMEN1KMT2ANOS2CYP2D6 | |
| SCHEMBL20017320 | 0.75 | KDM1A (0.54) | LMNAHSD17B10ESR1ESR2MEN1 | |
| SCHEMBL22043774 | 0.74 | NOS3 (0.48) | LMNAHSD17B10ESR1ESR2MEN1 | |
| SCHEMBL7717291 | 0.71 | KDM1A (0.38) | LMNAHSD17B10ESR1ESR2MEN1 | |
| SCHEMBL18938347 | 0.69 | KMT2A (0.61) | HSD17B10MEN1KMT2ACYP2D6HIF1A | |
| SCHEMBL22044257 | 0.66 | CYP2D6 (0.66) | LMNAMEN1KMT2ACYP2D6HIF1A | |
| SCHEMBL29506425 | 0.66 | L3MBTL1 (0.41) | LMNANOS2HIF1ANOS3 | |
| SCHEMBL28038711 | 0.65 | KMT2A (0.54) | LMNAHSD17B10ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |