Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384384 | 0.90 | MAPT (0.61) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7722388 | 0.88 | ELANE (0.44) | MAPTPOLBPKMELANEALDH1A1 | |
| SCHEMBL7721780 | 0.86 | MAPT (0.50) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7720716 | 0.86 | MAPT (0.50) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7724564 | 0.85 | MAPT (0.56) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7717473 | 0.85 | KMT2A (0.43) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7720737 | 0.84 | LMNA (0.59) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7722416 | 0.84 | MAPT (0.54) | MAPTPOLBPKMELANELMNA | |
| SCHEMBL7690064 | 0.81 | ALDH1A1 (0.40) | MAPTELANEKMT2AALDH1A1MEN1 | |
| SCHEMBL7720746 | 0.79 | ELANE (0.64) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |