Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384384 | 0.94 | MAPT (0.61) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7722416 | 0.88 | MAPT (0.54) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7724552 | 0.87 | ELANE (0.45) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7721788 | 0.87 | MAPT (0.44) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7724564 | 0.87 | MAPT (0.56) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7724559 | 0.86 | PRSS1 (0.48) | MAPTKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL7720716 | 0.85 | MAPT (0.50) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7724562 | 0.85 | KMT2A (0.51) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7721780 | 0.85 | MAPT (0.50) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL7717451 | 0.84 | MAPT (0.53) | LMNAMAPTPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |