Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.35 |
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717534 | 1.00 | MTNR1B (0.35) | MTNR1BACHEMTNR1AKDM4EKMT2A | |
| SCHEMBL7717555 | 0.82 | SCN9A (0.38) | MTNR1BMTNR1A | |
| SCHEMBL7719303 | 0.82 | SCN9A (0.38) | MTNR1BMTNR1A | |
| SCHEMBL7263724 | 0.81 | ACHE (0.48) | ACHE | |
| SCHEMBL7715098 | 0.81 | ACHE (0.48) | ACHE | |
| SCHEMBL7718518 | 0.78 | MTNR1B (0.36) | MTNR1BKMT2A | |
| SCHEMBL7721427 | 0.78 | MTNR1B (0.36) | MTNR1BKMT2A | |
| SCHEMBL7709306 | 0.78 | MTNR1B (0.36) | MTNR1BKMT2A | |
| SCHEMBL7259713 | 0.74 | HCRTR1 (0.39) | ACHE | |
| SCHEMBL7715113 | 0.74 | HCRTR1 (0.39) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |