Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732077 | 0.67 | KDM4E (0.37) | RAB9ANPC1SMN1; SMN2NPSR1ALDH1A1 | |
| Styrene SCHEMBL28077225 | 0.65 | ALDH1A1 (0.52) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| Allylbenzene SCHEMBL10897848 | 0.64 | L3MBTL1 (0.49) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| Biphenyl SCHEMBL7611759 | 0.63 | RAB9A (0.74) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| Biphenyl SCHEMBL11881576 | 0.63 | RAB9A (0.74) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| SCHEMBL17189693 | 0.62 | RAB9A (0.47) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| Benzene SCHEMBL29120356 | 0.61 | TSHR (0.55) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| Cyclopropane Carboxylic Acid SCHEMBL27805840 | 0.61 | TSHR (0.55) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| Toluene SCHEMBL28973335 | 0.60 | RAB9A (0.53) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 | |
| SCHEMBL3519807 | 0.60 | RAB9A (0.48) | RAB9ANPC1AKR1C3AKR1C1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380220-B1 | THERAPY OF NEURODEGENERATIVE DISEASES AND NEURONAL INJURIES WHICH ARE CASUED BY ISCHEMIA, TRAUMA OR MASSIVE HEMORRHAGES | ABBOTT LABORATORIES | 2002-04-30 | — | — | US | disclosed |