Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719244 | 0.99 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAASLC6A4SLC6A3 | |
| SCHEMBL6862148 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SLC6A4NTSR1MITFSMN1; SMN2 | |
| SCHEMBL7718161 | 0.84 | ALDH1A1 (0.60) | ALDH1A1SLC6A4SLC6A3SLC6A2NTSR1 | |
| SCHEMBL12123573 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EGAASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL31052904 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4EGAASLC6A4SLC6A3 | |
| SCHEMBL6862360 | 0.79 | SLC6A4 (0.69) | ALDH1A1SLC6A4SLC6A3SLC6A2NTSR1 | |
| SCHEMBL6864368 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4ESLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7717232 | 0.79 | LMNA (0.48) | ALDH1A1KDM4EMITFSMN1; SMN2HTT | |
| SCHEMBL7718661 | 0.77 | LMNA (0.53) | ALDH1A1KDM4EGAASLC6A4SLC6A3 | |
| SCHEMBL7718149 | 0.77 | LMNA (0.46) | ALDH1A1KDM4EMITFSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |