Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717232 | 0.99 | LMNA (0.48) | LMNAPOLBGCGRALDH1A1SMN1; SMN2 | |
| SCHEMBL10708108 | 0.84 | LMNA (0.49) | LMNAPOLBGCGRSLC6A9KDM2B | |
| SCHEMBL7718161 | 0.80 | ALDH1A1 (0.60) | LMNAPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10706138 | 0.80 | HRH3 (0.52) | LMNAPOLBGCGRALDH1A1NR4A1 | |
| SCHEMBL6862148 | 0.79 | ALDH1A1 (0.58) | LMNAALDH1A1SMN1; SMN2MAPTABCB1 | |
| SCHEMBL7718668 | 0.79 | OPRK1 (0.45) | ALDH1A1SMN1; SMN2KDM4EABCB1HTT | |
| SCHEMBL10707183 | 0.78 | HRH3 (0.55) | LMNAPOLBGCGRALDH1A1NR4A1 | |
| SCHEMBL7719244 | 0.78 | ALDH1A1 (0.52) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7718155 | 0.77 | ALDH1A1 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7719730 | 0.73 | GSK3B (0.43) | LMNAALDH1A1SMN1; SMN2MAPTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |