Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718661 | 0.85 | LMNA (0.53) | SLC6A4MEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL10672554 | 0.84 | SLC6A4 (0.51) | SLC6A4MEN1HPGDTSHRKMT2A | |
| SCHEMBL6862148 | 0.84 | ALDH1A1 (0.58) | SLC6A4MEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL7719212 | 0.83 | SLC6A4 (0.48) | SLC6A4HRH3SIGMAR1CHRM2ADRA2B | |
| SCHEMBL6862360 | 0.83 | SLC6A4 (0.69) | SLC6A4KMT2AHRH3SIGMAR1CHRM2 | |
| SCHEMBL7718161 | 0.82 | ALDH1A1 (0.60) | SLC6A4MEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL9720545 | 0.80 | CHRM2 (0.70) | SLC6A4MEN1HPGDTSHRKMT2A | |
| SCHEMBL6864368 | 0.80 | ALDH1A1 (0.62) | SLC6A4MEN1HPGDKMT2AHRH3 | |
| Lanperisone SCHEMBL5819917 | 0.79 | CHRM2 (0.68) | SLC6A4MEN1HPGDTSHRKMT2A | |
| Lanperisone SCHEMBL570832 | 0.79 | CHRM2 (0.68) | SLC6A4MEN1HPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |