Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862148 | 0.87 | ALDH1A1 (0.58) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL7718161 | 0.85 | ALDH1A1 (0.60) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL6864372 | 0.84 | ALDH1A1 (0.44) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL6862360 | 0.83 | SLC6A4 (0.69) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL7718666 | 0.83 | SLC6A4 (0.49) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL6864368 | 0.80 | ALDH1A1 (0.62) | SLC6A4ALDH1A1HTTCHRM2ADRA2B | |
| SCHEMBL7717254 | 0.78 | SLC6A4 (0.43) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL7713723 | 0.78 | SLC6A4 (0.43) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL7718150 | 0.78 | SLC6A4 (0.43) | SLC6A4ALDH1A1RAB9AHTTATM | |
| SCHEMBL7719730 | 0.77 | GSK3B (0.43) | SLC6A4ALDH1A1RAB9AHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |