Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719008 | 1.00 | L3MBTL1 (0.38) | L3MBTL1TOP1KDM4EMEN1ABCB11 | |
| SCHEMBL7715986 | 0.87 | L3MBTL1 (0.36) | L3MBTL1KDM4EMEN1ABCB11MAPT | |
| SCHEMBL7715985 | 0.87 | L3MBTL1 (0.36) | L3MBTL1KDM4EMEN1ABCB11MAPT | |
| SCHEMBL7715989 | 0.83 | BACE1 (0.33) | L3MBTL1TOP1KDM4EMEN1ABCB11 | |
| SCHEMBL31170532 | 0.76 | L3MBTL1 (0.49) | L3MBTL1MAPK1SYK | |
| SCHEMBL24208084 | 0.75 | BACE1 (0.42) | L3MBTL1MAPK1BACE1SYK | |
| SCHEMBL13460058 | 0.75 | CCR6 (0.41) | L3MBTL1BACE1SYK | |
| SCHEMBL1626511 | 0.73 | L3MBTL1 (0.48) | L3MBTL1MAPK1KMT2ASYK | |
| SCHEMBL25211503 | 0.73 | L3MBTL1 (0.48) | L3MBTL1MAPTMAPK1SYK | |
| SCHEMBL1554885 | 0.71 | SYK (0.51) | L3MBTL1MAPTBACE1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384026-B1 | Macrocyclic polyamine lactones and derivatives thereof and their use as arthropod repellents | CORNELL RESEARCH FOUNDATION, INC. | 2002-05-07 | — | — | US | disclosed |
| EP-1067921-A4 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RES FOUNDATION INC (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1067921-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051222-A9 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RES FOUNDATION INC (US) | 1999-12-02 | — | — | WO | disclosed |
| WO-1999051222-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-14 | — | — | WO | disclosed |