Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715986 | 1.00 | L3MBTL1 (0.36) | L3MBTL1BTN3A1MAPTPOLBGAA | |
| SCHEMBL7719007 | 0.87 | L3MBTL1 (0.38) | L3MBTL1MAPTKDM4EMEN1ABCB11 | |
| SCHEMBL7719008 | 0.87 | L3MBTL1 (0.38) | L3MBTL1MAPTKDM4EMEN1ABCB11 | |
| SCHEMBL7805334 | 0.84 | EPHX2 (0.33) | L3MBTL1MAPTPOLBKDM4EMEN1 | |
| SCHEMBL7719949 | 0.84 | EPHX2 (0.33) | L3MBTL1MAPTPOLBKDM4EMEN1 | |
| SCHEMBL7715989 | 0.78 | BACE1 (0.33) | L3MBTL1MAPTKDM4EMEN1ABCB11 | |
| SCHEMBL7718969 | 0.77 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL21959487 | 0.75 | ALDH1A1 (0.37) | L3MBTL1BTN3A1MAPK1 | |
| SCHEMBL25182464 | 0.75 | LTA4H (0.47) | L3MBTL1MAPK1 | |
| SCHEMBL7308118 | 0.74 | ALDH1A1 (0.46) | L3MBTL1BTN3A1KDM4EMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384026-B1 | Macrocyclic polyamine lactones and derivatives thereof and their use as arthropod repellents | CORNELL RESEARCH FOUNDATION, INC. | 2002-05-07 | — | — | US | disclosed |
| EP-1067921-A4 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RES FOUNDATION INC (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1067921-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051222-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-14 | — | — | WO | disclosed |