Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056702 | 0.95 | MGLL (0.51) | KMT2AMGLLALDH1A1HPGDMEN1 | |
| SCHEMBL3619558 | 0.95 | MGLL (0.51) | KMT2AMGLLALDH1A1HPGDMEN1 | |
| SCHEMBL23307970 | 0.88 | KMT2A (0.47) | KMT2AMGLLALDH1A1HPGDMEN1 | |
| SCHEMBL18684993 | 0.87 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1LMNATP53 | |
| SCHEMBL8654472 | 0.82 | ALDH1A1 (0.50) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL19426454 | 0.82 | MGLL (0.45) | KMT2AMGLLALDH1A1LMNAPTGS2 | |
| SCHEMBL542087 | 0.81 | ALDH1A1 (0.49) | KMT2AALDH1A1HPGDMEN1GAA | |
| SCHEMBL8082873 | 0.81 | GAA (0.51) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL13172128 | 0.81 | ALDH1A1 (0.40) | KMT2AMGLLALDH1A1HPGDMEN1 | |
| SCHEMBL7719024 | 0.80 | CYP3A4 (0.48) | KMT2AMGLLALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384264-B1 | NITRATION OF AN AROMATIC ALDEHYDE/KETONE TO AN O-NITRO DERIVATIVE AND REDUCING IT TO AN ALCOHOL, REACTING THE ALCOHOL WITH A MONO/DIISOCYANATES TO PROVIDE A 2-NITROBENZYL URETHANE CAPABLE OF GENERATING FREE AMINES UPON IRRADIATION | AGFA-GEVAERT (BE) | 2002-05-07 | — | — | US | disclosed |
| US-6171756-B1 | SOLVENT SOLUBLE ORGANIC PHOTOPRECURSORS OF AMINES FOR USE IN PHOTOSENSITIVE IMAGING SYSTEMS, SAID PHOTOPRECURSORS GENERATING FREE AMINES ON EXPOSURE TO LONG WAVELENGTH UV OR VISIBLE RADIATION, COMPRISING PHOTOLABILE 2-NITROBENZYL GROUPS | AFGA-GEVAERT, N.V. (BE) | 2001-01-09 | — | — | US | disclosed |
| EP-0926555-A1 | Photoactive materials applicable to imaging systems. | AGFA-GEVAERT N.V. (BE) | 1999-06-30 | — | — | EP | disclosed |