Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721427 | 0.79 | MTNR1B (0.36) | MTNR1BSCN9AKMT2ANPY1R | |
| SCHEMBL7718518 | 0.79 | MTNR1B (0.36) | MTNR1BSCN9AKMT2ANPY1R | |
| SCHEMBL7709306 | 0.79 | MTNR1B (0.36) | MTNR1BSCN9AKMT2ANPY1R | |
| SCHEMBL7717555 | 0.75 | SCN9A (0.38) | MTNR1BSCN9ANPY1R | |
| SCHEMBL7719303 | 0.75 | SCN9A (0.38) | MTNR1BSCN9ANPY1R | |
| SCHEMBL3532957 | 0.68 | TAS1R3 (0.44) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2629484 | 0.68 | TAS1R3 (0.44) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL31730795 | 0.67 | NR1H2 (0.40) | SCN9ANPY1R | |
| SCHEMBL31730505 | 0.67 | FPR2 (0.46) | SCN9ANPY1R | |
| SCHEMBL13260050 | 0.67 | XIAP (0.59) | MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |