Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862148 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7718161 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7719212 | 0.77 | SLC6A4 (0.48) | CYP3A4CYP2C9ALDH1A1HTTRAB9A | |
| SCHEMBL6864372 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7717232 | 0.74 | LMNA (0.48) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7718645 | 0.74 | ALDH1A1 (0.37) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7718155 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7713723 | 0.73 | SLC6A4 (0.43) | ALDH1A1HTTRAB9ASMN1; SMN2MITF | |
| SCHEMBL7713750 | 0.73 | ALDH1A1 (0.44) | CYP3A4CYP2C9ALDH1A1HTTRAB9A | |
| SCHEMBL7718210 | 0.73 | KMT2A (0.50) | ALDH1A1HTTRAB9ASMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |