Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.52 |
| ▸ | CCR3 | P51677 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719896 | 1.00 | SIGMAR1 (0.52) | SIGMAR1CCR3NPC1PRCPALDH1A1 | |
| SCHEMBL7729788 | 0.92 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL7729790 | 0.92 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL7729835 | 0.79 | SIGMAR1 (0.56) | SIGMAR1CCR3NPC1CCR5 | |
| SCHEMBL7729841 | 0.79 | SIGMAR1 (0.56) | SIGMAR1CCR3NPC1CCR5 | |
| SCHEMBL7729514 | 0.77 | DRD2 (0.45) | SIGMAR1CCR3 | |
| SCHEMBL7729521 | 0.77 | DRD2 (0.45) | SIGMAR1CCR3 | |
| SCHEMBL6618321 | 0.74 | NOS1 (0.55) | SIGMAR1CCR3CCR5 | |
| SCHEMBL31486979 | 0.71 | SIGMAR1 (0.71) | SIGMAR1CCR3 | |
| SCHEMBL7719812 | 0.71 | NR4A2 (0.48) | SIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |