Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729788 | 1.00 | SIGMAR1 (0.57) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL7719892 | 0.92 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL7719896 | 0.92 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL7724034 | 0.77 | SIGMAR1 (0.62) | SIGMAR1DRD4 | |
| SCHEMBL7724040 | 0.77 | SIGMAR1 (0.62) | SIGMAR1DRD4 | |
| SCHEMBL7723974 | 0.75 | SIGMAR1 (0.53) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL7723985 | 0.75 | SIGMAR1 (0.53) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL28762171 | 0.73 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL6620343 | 0.73 | NOS1 (0.65) | SIGMAR1 | |
| SCHEMBL15636721 | 0.72 | SIGMAR1 (0.52) | SIGMAR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |