Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719940 | 0.85 | ALDH1A1 (0.56) | HTTMAPK1LMNAPOLBL3MBTL1 | |
| SCHEMBL12674480 | 0.85 | ALDH1A1 (0.74) | HTTLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL12674581 | 0.83 | ALDH1A1 (0.72) | HTTLMNAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14263406 | 0.82 | POLB (0.67) | HTTMAPK1LMNAPOLBATM | |
| SCHEMBL21813105 | 0.81 | POLB (0.61) | HTTMAPK1LMNAPOLBAPOBEC3A | |
| SCHEMBL15683000 | 0.81 | POLB (0.65) | HTTMAPK1LMNAPOLBATM | |
| SCHEMBL6224554 | 0.81 | PKM (0.67) | HTTMAPK1LMNAPOLBATM | |
| SCHEMBL266849 | 0.81 | PKM (0.67) | HTTMAPK1LMNAPOLBATM | |
| SCHEMBL2379666 | 0.81 | POLB (0.65) | HTTMAPK1LMNAPOLBATM | |
| SCHEMBL3936569 | 0.79 | POLB (1.00) | HTTLMNAPOLBATMAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388022-B1 | POLYSTYRENE | TAKEDA CHEMICAL INDUSTIRES, LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0985662-A2 | Linker binding carriers for organic synthesis, their production and use | Takeda Chemical Industries, Ltd. (JP) | 2000-03-15 | — | — | EP | disclosed |