Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674480 | 0.86 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL7719944 | 0.85 | HTT (0.68) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL12674581 | 0.85 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL24762195 | 0.80 | LMNA (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL29764391 | 0.80 | LMNA (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL4526586 | 0.78 | POLB (0.69) | ALDH1A1SMN1; SMN2LMNATSHRPKM | |
| SCHEMBL56599 | 0.75 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL10726996 | 0.75 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL31315849 | 0.72 | PKM (0.70) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL10860773 | 0.72 | PKM (0.77) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388022-B1 | POLYSTYRENE | TAKEDA CHEMICAL INDUSTIRES, LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0985662-A2 | Linker binding carriers for organic synthesis, their production and use | Takeda Chemical Industries, Ltd. (JP) | 2000-03-15 | — | — | EP | disclosed |