Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.53 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064805 | 0.84 | SMPD1 (0.50) | ENPP2SLC6A5LPAR1LPAR4LPAR5 | |
| SCHEMBL3332099 | 0.84 | SMPD1 (0.50) | ENPP2SLC6A5LPAR1LPAR4LPAR5 | |
| SCHEMBL9130238 | 0.84 | SMPD1 (0.50) | ENPP2SLC6A5LPAR1LPAR4LPAR5 | |
| SCHEMBL5699819 | 0.83 | FABP3 (0.41) | SLC6A5FABP3 | |
| SCHEMBL23123577 | 0.83 | PRKCE (0.60) | ENPP2SLC6A5LPAR1LPAR4LPAR5 | |
| SCHEMBL1613621 | 0.83 | PRKCE (0.60) | ENPP2SLC6A5LPAR1LPAR4LPAR5 | |
| SCHEMBL7624924 | 0.81 | ALDH1A1 (0.61) | ENPP2LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL30668211 | 0.81 | ENPP2 (0.75) | ENPP2LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL6120421 | 0.80 | SLC6A5 (0.51) | ENPP2SLC6A5LPAR1LPAR4LPAR5 | |
| SCHEMBL24681827 | 0.79 | FABP3 (0.76) | ENPP2LPAR1P2RY10GPR34FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020142046-A1 | Protein particles for therapeutic and diagnostic use | YEN, RICHARD C.K. | 2002-10-03 | — | — | US | disclosed |
| US-6391343-B1 | PARTICLE COMPRISING FIBRINOGEN BOUND ON SURFACE OF ALBUMIN MATRIX, CAPABLE OF CO-AGGREGATION WITH PLATELETS, AND OF AGGREGATION IN SOLUTION CONTAINING SOLUBLE FIBRINOGEN AT CONCENTRATION NOT CAPABLE OF CLOT FORMATION BY ITSELF | HEMOSPHERE, INC. | 2002-05-21 | — | — | US | disclosed |
| US-5945033-A | ALBUMIN, HEMOGLOBIN MIXTURE; STABILITY | HEMOSPHERE, INC. (US) | 1999-08-31 | — | — | US | disclosed |
| US-5725804-A | ALBUMIN PARTICLES STABLE TO RESOLUBILIZATION, POLYOXYETHYLENE GLYCOL, ALCOHOL | HEMOSPHERE, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5616311-A | AQUEOUS ALBUMIN SUSPENSION STABILIZED BY HEMOGLOBIN PARTICLES | HEMOSPHERE, INC. (US) | 1997-04-01 | — | — | US | disclosed |