Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344111 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL712851 | 0.82 | MAPT (0.57) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL1018611 | 0.80 | LMNA (0.61) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL1462829 | 0.80 | CA2 (0.60) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL5674108 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TDP1ALOX15KDM4EHSD17B10 | |
| SCHEMBL9336200 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1KDM4EHSD17B10MAPT | |
| SCHEMBL2514721 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL11028304 | 0.75 | MAPT (0.46) | ALDH1A1CYP3A4ALOX15KDM4EHSD17B10 | |
| SCHEMBL11025338 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4KDM4EHSD17B10 | |
| SCHEMBL5673659 | 0.75 | HSD17B10 (0.52) | ALDH1A1TDP1CYP3A4ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376656-B1 | DISAZO DYES, TRIAZINE DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-23 | — | — | US | disclosed |
| EP-0652262-B1 | Reactive dyestuffs, their preparation and use | BAYER AG (DE) | 2000-07-12 | — | — | EP | disclosed |
| US-6025478-A | HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS | BAYER AG (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0641838-B1 | Reactive dye-stuffs on basis of a substituted barbituric acid | BAYER AG (DE) | 1999-11-10 | — | — | EP | disclosed |
| EP-0542082-B1 | Process for continuously reacting difluortriazinyl compounds with amines | BAYER AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| EP-0497174-B1 | Bifunctional reactive dyes containing vinylsulfone/pyrimidine groups | BAYER AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0568876-B1 | Reactive dyes, their preparation and their use | BAYER AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5463031-A | Printing, dyeing cellulose and organonitrogen compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0652262-A1 | Reactive dyestuffs, their preparation and use | BAYER AG (DE) | 1995-05-10 | — | — | EP | disclosed |
| EP-0174275-A1 | Process for dyeing or printing fibrous textile materials with reactive dyes | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |
| EP-0167490-A1 | Reactive dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1986-01-08 | — | — | EP | disclosed |
| EP-0079563-B1 | WATER SOLUBLE 1:2 METAL COMPLEX AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0141776-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-05-15 | — | — | EP | disclosed |
| EP-0134193-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-03-13 | — | — | EP | disclosed |
| EP-0133843-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-03-06 | — | — | EP | disclosed |
| EP-0128340-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0040806-B1 | WATER-SOLUBLE, COLOURED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0079563-A2 | Water soluble 1:2 metal complex azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0040806-A2 | Water-soluble, coloured compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-02 | — | — | EP | disclosed |