Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 2/20 | 0.44 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | PPIG | Q13427 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321166 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL11039440 | 0.85 | LMNA (0.53) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL1246313 | 0.84 | L3MBTL1 (0.52) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL5700957 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL1244623 | 0.83 | TSHR (0.55) | ALDH1A1KDM4ETSHRF2F10 | |
| SCHEMBL1244581 | 0.83 | ALOX15 (0.52) | ALDH1A1KDM4EHTTMAPTNPC1 | |
| SCHEMBL5691331 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL1767983 | 0.82 | LMNA (0.50) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| SCHEMBL5670458 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHTTLMNACYP1A2 | |
| Butane SCHEMBL5272274 | 0.81 | L3MBTL1 (0.50) | ALDH1A1KDM4EHTTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020077491-A1 | Methods for forming combinatorial libraries combining amide bond formation with epoxide opening | NEOGENESIS PHARMACEUTICALS, INC. | 2002-06-20 | — | — | US | disclosed |
| WO-2002020436-A2 | METHODS FOR FORMING COMBINATORIAL LIBRARIES COMBINING AMIDE BOND FORMATION WITH EPOXIDE OPENING | NEOGENESIS PHARMACEUTICALS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077491-A1 | Methods for forming combinatorial libraries combining amide bond formation with epoxide opening | EPHX2, COASY, EPHX1 | ALDH1A1 221/4885KDM4E 2079/4885HTT 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.