Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171022 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1ALOX15CYP3A4MAPT | |
| SCHEMBL29050819 | 0.85 | GABRP (0.41) | NNMTKDM4EALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL9315419 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1ALOX15CYP3A4MAPT | |
| Nitrous Acid SCHEMBL28913581 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1ALOX15CYP3A4MAPT | |
| SCHEMBL2397267 | 0.80 | NNMT (0.44) | NNMTKDM4EL3MBTL1SMN1; SMN2PSMD14 | |
| SCHEMBL31314588 | 0.79 | LMNA (0.41) | NNMTKDM4EALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL12350329 | 0.79 | NNMT (0.40) | NNMTKDM4EALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL12350259 | 0.79 | NNMT (0.40) | NNMTALDH1A1TSHRSMN1; SMN2PSMD14 | |
| SCHEMBL28913580 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1ALOX15CYP3A4MAPT | |
| SCHEMBL19857468 | 0.76 | GABRP (0.44) | KDM4EALDH1A1ALOX15CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728744-B1 | Process for the preparation of carboxylic acids of nitrogen-containing heterocycles | LONZA AG (CH) | 2002-04-10 | — | — | EP | disclosed |
| EP-0627422-B1 | Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles | LONZA AG (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0728744-A2 | Process for the preparation of carboxylic acids of nitrogen-containing heterocycles | LONZA A.G. (CH) | 1996-08-28 | — | — | EP | disclosed |
| EP-0627422-A2 | Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles, as well as their use | LONZA A.G. (CH) | 1994-12-07 | — | — | EP | disclosed |