SCHEMBL2397267

SCHEMBL2397267

NC(=O)c1cnc(C(N)=O)c(C(N)=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 11/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PSMD14 O00487 1/20 0.40
STAMBP O95630 1/20 0.40
COPS5 Q92905 1/20 0.40
HPGDS O60760 2/20 0.39
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
F7 P08709 1/20 0.35
F3 P13726 1/20 0.35
SARM1 Q6SZW1 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
SIRT6 Q8N6T7 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
SIRT3 Q9NTG7 1/20 0.35
SIRT5 Q9NXA8 1/20 0.35
SIRT4 Q9Y6E7 1/20 0.35
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7720516 0.80 NNMT (0.41) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL29050819 0.80 GABRP (0.41) NNMTSMN1; SMN2PSMD14LMNAKDM4E
SCHEMBL28617172 0.78 LMNA (0.44) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL27372639 0.78 PARP1 (0.51) NNMTSMN1; SMN2SIRT3MKNK1MKNK2
SCHEMBL2219734 0.78 NNMT (0.46) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
Hydrochloric Acid SCHEMBL28641941 0.76 NNMT (0.44) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL30478243 0.75 NNMT (0.41) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL28285907 0.75 NNMT (0.41) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL1503085 0.75 NNMT (0.40) NNMTSMN1; SMN2PSMD14STAMBPCOPS5
SCHEMBL31327199 0.73 NNMT (0.50) NNMTSMN1; SMN2HPGDSKDM4ESIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8702854-B2 Azaphthalocyanines and their use in ink-jet printing FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
EP-2376577-B1 AZAPHTHALOCYANINES AND THEIR USE IN INK-JET PRINTING FUJIFILM IMAGING COLORANTS LTD (GB) 2012-12-26 EP disclosed
CN-102264842-A Azaphthalocyanines and their use in ink-jet printing 2011-11-30 CN disclosed
EP-2376577-A2 AZAPHTHALOCYANINES AND THEIR USE IN INK-JET PRINTING FUJIFILM Imaging Colorants Limited (GB) 2011-10-19 EP disclosed
US-20110234687-A1 Azaphthalocyanines and Their Use in Ink-Jet Printing Fujifilm Imaging Colorants, Limited (GB) 2011-09-29 US disclosed
WO-2010070313-A2 AZAPHTHALOCYANINES AND THEIR USE IN INK-JET PRINTING FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110234687-A1 Azaphthalocyanines and Their Use in Ink-Jet Printing JMJD1C, PCBP1, ZYX NNMT 639/4885SMN1; SMN2 2718/4885PSMD14 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.