Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724572 | 0.90 | ELANE (0.44) | MAPTCYP11B1CYP11B2TDP1L3MBTL1 | |
| SCHEMBL7721785 | 0.88 | MAPT (0.44) | MAPTPOLBPKMCYP11B1CYP11B2 | |
| SCHEMBL7722379 | 0.87 | KMT2A (0.43) | MAPTCYP11B1CYP11B2TDP1L3MBTL1 | |
| SCHEMBL7722385 | 0.86 | LMNA (0.51) | MAPTPOLBPKMCYP11B1CYP11B2 | |
| SCHEMBL7690693 | 0.86 | ENPP1 (0.42) | MAPTCYP11B1CYP11B2TDP1ALDH1A1 | |
| SCHEMBL7720733 | 0.85 | ELANE (0.51) | MAPTPOLBPKMTDP1ALDH1A1 | |
| SCHEMBL7696064 | 0.84 | ENPP1 (0.41) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7720716 | 0.84 | MAPT (0.50) | MAPTPOLBPKMTDP1L3MBTL1 | |
| SCHEMBL9015170 | 0.82 | ALDH1A1 (0.55) | MAPTTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL6739638 | 0.80 | TP53 (0.46) | MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |