Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720726 | 0.90 | ELANE (0.44) | MAPTPOLBPKMELANECYP11B1 | |
| SCHEMBL7720712 | 0.88 | MAPT (0.44) | MAPTPOLBPKMELANEPTGS2 | |
| SCHEMBL7721776 | 0.87 | KMT2A (0.43) | MAPTPKMELANEPTGS2CYP11B1 | |
| SCHEMBL7722385 | 0.86 | LMNA (0.51) | MAPTPOLBPKMELANEPTGS2 | |
| SCHEMBL7695885 | 0.86 | MMP2 (0.37) | ELANECYP11B1CYP11B2KMT2AMEN1 | |
| SCHEMBL7720733 | 0.85 | ELANE (0.51) | MAPTPOLBPKMELANEPTGS2 | |
| SCHEMBL7690054 | 0.84 | MMP2 (0.40) | CYP11B1CYP11B2LMNAKMT2AMEN1 | |
| SCHEMBL7721780 | 0.84 | MAPT (0.50) | MAPTPOLBPKMELANEPTGS2 | |
| SCHEMBL6742537 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL7717471 | 0.80 | MAPT (0.51) | MAPTPOLBPKMELANEPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |