Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724550 | 0.89 | ELANE (0.53) | ELANEMAPTPOLBPKMPTGS2 | |
| SCHEMBL7722385 | 0.88 | LMNA (0.51) | ELANEMAPTPOLBPKMPTGS2 | |
| SCHEMBL7721805 | 0.86 | ELANE (0.53) | ELANEMAPTPTGS2ALDH1A1LMNA | |
| SCHEMBL7721785 | 0.85 | MAPT (0.44) | ELANEMAPTPOLBPKMPTGS2 | |
| SCHEMBL7720712 | 0.85 | MAPT (0.44) | ELANEMAPTPOLBPKMPTGS2 | |
| SCHEMBL7695453 | 0.84 | MMP2 (0.40) | PTGS2ALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL7724566 | 0.83 | MAPT (0.57) | ELANEMAPTPOLBPKMPTGS2 | |
| SCHEMBL546386 | 0.83 | CES2 (0.45) | MAPTALDH1A1LMNAMAPK1MEN1 | |
| SCHEMBL7696242 | 0.82 | MMP2 (0.43) | PTGS2ALDH1A1KMT2ACES2CES1 | |
| SCHEMBL384364 | 0.82 | CES2 (0.51) | MAPTPTGS2ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |