SCHEMBL7724559

SCHEMBL7724559

Cc1ccc(C(=O)Oc2ccc(S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)c3ccc(OC(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 4/20 0.48
ACR P10323 4/20 0.48
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HSP90AA1 P07900 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
KMT2A Q03164 10/20 0.43
MEN1 O00255 2/20 0.43
PLG P00747 1/20 0.42
GAA P10253 1/20 0.42
GBA1 P04062 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7720737 0.86 LMNA (0.59) MAPTKDM4ESMN1; SMN2KMT2AMEN1
SCHEMBL7721707 0.86 MAPT (0.50) MAPTKDM4ESMN1; SMN2KMT2AMEN1
SCHEMBL7724552 0.82 ELANE (0.45) MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL7724562 0.82 KMT2A (0.51) MAPTSMN1; SMN2KMT2AMEN1GAA
SCHEMBL36092 0.82 GAA (0.48) PRSS1MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL25491843 0.81 MAPT (0.58) PRSS1ACRMAPTKDM4EHSP90AA1
SCHEMBL384384 0.79 MAPT (0.61) MAPTKDM4EHSP90AA1SMN1; SMN2KMT2A
SCHEMBL383061 0.78 KMT2A (0.49) MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL7688694 0.78 CA2 (0.42) MAPTSMN1; SMN2KMT2AMEN1GAA
SCHEMBL9663961 0.78 PRSS1 (0.69) PRSS1ACRSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395446-B1 CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-28 US disclosed