Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721773 | 0.75 | HPGD (0.52) | ALDH1A1TSHRHSD17B10L3MBTL1HPGD | |
| SCHEMBL19153758 | 0.75 | CYP1A2 (0.48) | ALDH1A1TSHRHSD17B10L3MBTL1HPGD | |
| SCHEMBL31711763 | 0.74 | — | — | |
| SCHEMBL18606193 | 0.72 | HPRT1 (0.40) | ALDH1A1HSD17B10HPGDKDM4EPOLB | |
| Boric Acid SCHEMBL28912173 | 0.72 | CES2 (0.34) | — | |
| SCHEMBL7908123 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL13878089 | 0.70 | KEAP1 (0.50) | CRHBPCRHR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL30366320 | 0.70 | ALDH1A1 (0.39) | NFE2L2ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL2887670 | 0.70 | ALDH1A1 (0.39) | NFE2L2ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL28967827 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261573-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 Ontario Limited (CA) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001007386-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 ONTARIO LIMITED (CA) | 2001-02-01 | — | — | WO | disclosed |