Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545834 | 0.87 | NPC1 (0.59) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10518545 | 0.82 | ALDH1A1 (0.53) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3359452 | 0.79 | ALDH1A1 (0.50) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2468905 | 0.79 | MAOB (0.49) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL602068 | 0.79 | MAOB (0.55) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL602067 | 0.79 | MAOB (0.55) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL30605656 | 0.78 | MAOB (0.54) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL37410 | 0.78 | MAOB (0.54) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1556056 | 0.78 | MAOB (0.54) | MAOBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9614520 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423452-A | Rugoside intermediate, preparation method and application thereof | 江西青峰药业有限公司 | 2020-07-17 | — | — | CN | claimed |
| CN-111423452-A | Rugoside intermediate, preparation method and application thereof | 江西青峰药业有限公司 | 2020-07-17 | — | — | CN | disclosed |
| US-20160122383-A1 | Peptide Ligation | THE UNIVERSITY OF SYDNEY (AU) | 2016-05-05 | — | — | US | disclosed |
| EP-1119528-B1 | CHEMICAL CONSTRUCTS AND THEIR USES | GLAXO GROUP LTD (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1119528-A2 | CHEMICAL CONSTRUCTS AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020112-A2 | CHEMICAL CONSTRUCTS AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122383-A1 | Peptide Ligation | PTMS, PTMA, QPCTL | MAOB 1627/4885MEN1 3925/4885KMT2A 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.