Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518545 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTTSHRL3MBTL1HPGD | |
| SCHEMBL7721097 | 0.79 | MAOB (0.51) | ALDH1A1HTTTSHRL3MBTL1MAOB | |
| SCHEMBL77922 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL1058875 | 0.76 | MAPT (0.51) | ALDH1A1HTTTSHRTDP1MAOB | |
| SCHEMBL21545834 | 0.76 | NPC1 (0.59) | ALDH1A1HTTL3MBTL1TDP1HPGD | |
| SCHEMBL28424497 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL3125878 | 0.75 | MAOB (0.68) | ALDH1A1HTTTSHRHPGDMAOB | |
| SCHEMBL29546539 | 0.75 | ALDH3A1 (0.66) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL11745238 | 0.75 | ALDH3A1 (0.66) | ALDH1A1HTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL10961899 | 0.74 | PTPRF (0.59) | ALDH1A1L3MBTL1HPGDMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | GAO XIAOLIAN (US) | 2013-05-16 | — | — | US | disclosed |
| US-8076501-B2 | Photogenerated reagents | LC SCIENCES LC | 2011-12-13 | — | — | US | disclosed |
| US-20100137600-A1 | Photogenerated reagents | LC SCIENCES LC | 2010-06-03 | — | — | US | disclosed |
| US-7544829-B2 | Photogenerated reagents | LC SCIENCES LC | 2009-06-09 | — | — | US | disclosed |
| US-20080009630-A1 | Photogenerated reagents | LC SCIENCES LC | 2008-01-10 | — | — | US | disclosed |
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | disclosed |
| US-20060122408-A1 | Photogenerated reagents | LC SCIENCES LC | 2006-06-08 | — | — | US | disclosed |
| US-6965040-B1 | Photogenerated reagents | Gao, Xiaolian (US) | 2005-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885HTT 1804/4885TSHR 446/4885 |
| US-20080009630-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885HTT 1804/4885TSHR 446/4885 |
| US-20060122408-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885HTT 1804/4885TSHR 446/4885 |
| US-20100137600-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885HTT 1804/4885TSHR 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.