Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363128 | 0.85 | PDE10A (0.58) | PDE10ARAB9AALDH1A1LMNARXFP1 | |
| SCHEMBL6284250 | 0.82 | ALDH1A1 (0.55) | PDE10ARAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7721157 | 0.78 | SMN1; SMN2 (0.47) | RAB9AALDH1A1LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL9513257 | 0.77 | ALDH1A1 (0.54) | PDE10AALDH1A1LMNAMAPT | |
| SCHEMBL15723845 | 0.76 | KDM4E (0.58) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL5106665 | 0.75 | PDE10A (0.43) | PDE10ARAB9AALDH1A1LMNAHSD17B10 | |
| SCHEMBL7721150 | 0.75 | LMNA (0.51) | RAB9AALDH1A1LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL7721559 | 0.72 | SMN1; SMN2 (0.53) | RAB9AALDH1A1LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL9514685 | 0.70 | RAB9A (1.00) | RAB9AALDH1A1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7726932 | 0.70 | HSD17B10 (0.53) | RAB9AALDH1A1LMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |