Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 4/20 | 0.44 |
| ▸ | F13A1 | P00488 | 2/20 | 0.44 |
| ▸ | TGM1 | P22735 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698054 | 1.00 | BRD4 (0.54) | BRD4PKMCTSKCCR5TGM2 | |
| SCHEMBL24571569 | 0.94 | PKM (0.51) | BRD4PKMNAMPTKMT2AALDH1A1 | |
| SCHEMBL31437043 | 0.94 | PKM (0.51) | BRD4PKMNAMPTKMT2AALDH1A1 | |
| SCHEMBL12727844 | 0.87 | BRD4 (0.52) | BRD4SMN1; SMN2 | |
| SCHEMBL7719046 | 0.84 | TGM2 (0.50) | BRD4PKMCCR5TGM2F13A1 | |
| SCHEMBL7719040 | 0.84 | TGM2 (0.50) | BRD4PKMCCR5TGM2F13A1 | |
| SCHEMBL24711750 | 0.83 | EPHX2 (0.62) | PKMNAMPTKMT2AALDH1A1KDM4E | |
| SCHEMBL13188666 | 0.82 | ALOX5AP (0.49) | BRD4KMT2AALOX5APFEN1EPHX2 | |
| SCHEMBL24571611 | 0.82 | MBTD1 (0.52) | BRD4PKMNAMPTKMT2AALDH1A1 | |
| SCHEMBL24711657 | 0.82 | KMT2A (0.65) | PKMNAMPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |