Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.50 |
| ▸ | F13A1 | P00488 | 3/20 | 0.50 |
| ▸ | TGM1 | P22735 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719046 | 1.00 | TGM2 (0.50) | TGM2F13A1TGM1BRD4RORC | |
| SCHEMBL30990611 | 0.95 | PKM (0.52) | TGM2F13A1TGM1RORCPKM | |
| SCHEMBL24571914 | 0.84 | PKM (0.50) | TGM2F13A1TGM1RORCPKM | |
| SCHEMBL7721392 | 0.84 | BRD4 (0.54) | TGM2F13A1TGM1BRD4PKM | |
| SCHEMBL7698054 | 0.84 | BRD4 (0.54) | TGM2F13A1TGM1BRD4PKM | |
| SCHEMBL32665614 | 0.82 | MTNR1A (0.51) | KMT2AL3MBTL1 | |
| SCHEMBL32665295 | 0.82 | MTNR1A (0.51) | KMT2AL3MBTL1 | |
| SCHEMBL32665202 | 0.80 | CKS1B (0.52) | TSHRHTTKMT2AL3MBTL1 | |
| SCHEMBL24571938 | 0.80 | TGM2 (0.49) | TGM2F13A1TGM1RORCPKM | |
| SCHEMBL29640929 | 0.80 | TGM2 (0.49) | TGM2F13A1TGM1RORCPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |