Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GMNN | O75496 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.36 |
| ▸ | CCR6 | P51684 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451608 | 0.93 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL28911285 | 0.93 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL459592 | 0.93 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Acetic Acid SCHEMBL10386135 | 0.87 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL471887 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14673845 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL887140 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1974712 | 0.81 | MEN1 (0.34) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14675203 | 0.80 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14675164 | 0.80 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111770693-B | Foam control | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-05-26 | — | — | CN | disclosed |
| US-12590414-B2 | Paper and pulp foam control agent | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-03-31 | — | — | US | disclosed |
| EP-3764816-B1 | FOAM CONTROL IN FOOD | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-01-28 | — | — | EP | disclosed |
| EP-4504880-B1 | WATER BASED SEMI-SYNTHETIC METAL WORKING FLUID COMPOSITION CONTAINING A CYCLIC POLYFUNCTIONAL AMINE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-11-19 | — | — | EP | disclosed |
| US-20250339793-A1 | FOAM CONTROL AGENTS FORMED FROM POLYOL ESTER OF FATTY ACIDS (PEFAS) | RUBY BIO INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250313778-A1 | COMPOSITIONS FOR CLEANING METALS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-10-09 | — | — | US | disclosed |
| US-12410376-B2 | Water based semi-synthetic metal working fluid composition containing an alkyl alcohol amine | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-09-09 | — | — | US | disclosed |
| US-12364262-B2 | Water based semi-synthetic metal working fluid composition containing an aminopropenediol | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-07-22 | — | — | US | disclosed |
| EP-4284903-B1 | METAL WORKING FLUIDS BIOCIDE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-3856386-B1 | ALKYL ETHER AMINE FOAM CONTROL COMPOUNDS AND METHODS OF PROCESSING FOODSTUFFS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-05-28 | — | — | EP | disclosed |
| US-4253994-A | COATING FOR TIRES PRIOR TO CURING | NALCO CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4160742-A | USING AS DEEMULSIFIER A COPOLYMER OF ACRYLAMIDE AND METHYLACRYLAMIDOTRIMETHYLAMMONIUM CHLORIDE | CALGON CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4149983-A | 1,3,5-TRIS-(FURFURYL) HEXAHYDROTRIAZINE | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4147681-A | ACRYLAMIDE POLYMERS/; | CALGON CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4120815-A | Polymeric demulsifiers | CALGON CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |
| US-4077930-A | Self-inverting emulsions of dialkyldiallyl ammonium chloride polymers and copolymers | CALGON CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4051065-A | Apparatus for dissolving water soluble polymers and gums in water | NALCO CHEMICAL COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4021365-A | AMIDES | DIAMOND SHAMROCK CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |
| US-3990905-A | A BIS-AMIDE AND A HYDROCARBON OIL | NALCO CHEMICAL COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3959176-A | Non-foaming dispersing composition | DREW CHEMICAL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12364262-B2 | Water based semi-synthetic metal working fluid composition containing an aminopropenediol | ALAD, CYP17A1, AQP1 | ALDH1A1 2379/4885MEN1 775/4885KMT2A 2123/4885 |
| US-20250339793-A1 | FOAM CONTROL AGENTS FORMED FROM POLYOL ESTER OF FATTY ACIDS (PEFAS) | LIPA, PEF1, PNLIP | ALDH1A1 4265/4885MEN1 4000/4885KMT2A 2635/4885 |
| US-12590414-B2 | Paper and pulp foam control agent | DAGLA, PRF1, PNLIP | ALDH1A1 1401/4885MEN1 4406/4885KMT2A 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.