Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717779 | 0.94 | FFAR4 (0.57) | FFAR4FFAR1PIN1SIRT2SIRT1 | |
| SCHEMBL2327149 | 0.92 | FFAR4 (0.48) | FFAR4FFAR1PIN1ARSIRT2 | |
| SCHEMBL2327181 | 0.90 | PPARG (0.52) | FFAR4ARSIRT2SIRT1PPARG | |
| SCHEMBL9281680 | 0.88 | PDE3B (0.47) | FFAR4FFAR1SIRT2SIRT1PPARG | |
| SCHEMBL2332168 | 0.86 | FFAR4 (0.47) | FFAR4FFAR1PIN1SIRT2SIRT1 | |
| SCHEMBL2329776 | 0.86 | SIRT2 (0.51) | FFAR4ARSIRT2SIRT1PPARG | |
| SCHEMBL2211572 | 0.85 | G6PD (0.46) | FFAR4PPARGHRH3PPARAPDE3B | |
| SCHEMBL9281733 | 0.85 | PDE3B (0.47) | PPARGFABP4PPARAPDE3BPDE3A | |
| SCHEMBL4588629 | 0.85 | FAAH (0.47) | ARSIRT2SIRT1CHEK2PPARG | |
| SCHEMBL4590119 | 0.84 | LTB4R (0.48) | FFAR4FFAR1PPARGPPARAPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246808-A1 | 1,2-DIARYL BENZIMIDAZOLES FOR TREATING ILLNESSES ASSOCIATED WITH A MICROGLIA ACTIVATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051473-A1 | 1,2-DIARYL BENZIMIDAZOLES FOR TREATING ILLNESSES ASSOCIATED WITH A MICROGLIA ACTIVATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-19 | — | — | WO | disclosed |