Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722429 | 0.87 | POLB (0.46) | GLAKMT2AESR1SMN1; SMN2POLB | |
| SCHEMBL7695448 | 0.85 | ENPP3 (0.54) | GLAKMT2APOLBENPP3ENPP1 | |
| SCHEMBL7724555 | 0.84 | ELANE (0.39) | GLAKMT2ASMN1; SMN2POLBENPP3 | |
| SCHEMBL7696102 | 0.82 | ENPP3 (0.52) | POLBENPP3ENPP1ENPP2MMP1 | |
| SCHEMBL6735766 | 0.81 | S1PR5 (0.44) | RECQLMMP1TSHR | |
| SCHEMBL7693580 | 0.81 | ENPP3 (0.49) | KMT2APOLBENPP3ENPP1ENPP2 | |
| SCHEMBL7721693 | 0.81 | KMT2A (0.39) | GLAKMT2AESR1HIF1ARECQL | |
| SCHEMBL7717475 | 0.80 | KMT2A (0.45) | KMT2AESR1HIF1ARECQLSMN1; SMN2 | |
| SCHEMBL928962 | 0.80 | ALDH1A1 (0.46) | GLAKMT2ASMN1; SMN2POLBENPP3 | |
| SCHEMBL29904429 | 0.78 | POLB (0.41) | KMT2ASMN1; SMN2POLBENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |