SCHEMBL7696102

SCHEMBL7696102

CS(=O)(=O)Oc1ccc(S(=O)(=O)C(=[N+]=[N-])C(=O)C2CCCCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 13/20 0.52
ENPP1 P22413 12/20 0.52
ENPP2 Q13822 9/20 0.41
MMP2 P08253 2/20 0.40
MMP7 P09237 2/20 0.40
MMP9 P14780 2/20 0.40
MMP14 P50281 2/20 0.40
MMP1 P03956 1/20 0.40
STS P08842 1/20 0.38
MMP3 P08254 1/20 0.38
MMP8 P22894 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7695448 0.88 ENPP3 (0.54) ENPP3ENPP1ENPP2MMP2MMP7
SCHEMBL7722429 0.85 POLB (0.46) ENPP3ENPP1ENPP2POLB
SCHEMBL7693580 0.83 ENPP3 (0.49) ENPP3ENPP1ENPP2MMP2MMP7
SCHEMBL928962 0.83 ALDH1A1 (0.46) ENPP3ENPP1ENPP2POLB
SCHEMBL7724555 0.82 ELANE (0.39) ENPP3ENPP1ENPP2MMP2MMP7
SCHEMBL7721795 0.82 GLA (0.38) ENPP3ENPP1ENPP2MMP9MMP1
SCHEMBL29904429 0.80 POLB (0.41) ENPP3ENPP1ENPP2POLB
SCHEMBL8751838 0.80 ENPP3 (0.46) ENPP3ENPP1ENPP2
SCHEMBL6735766 0.80 S1PR5 (0.44) MMP1
SCHEMBL7696538 0.79 MMP2 (0.41) ENPP3ENPP1MMP2MMP7MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6338931-B1 PHOTOACID GENERATOR OF SULFONYLDIAZOMETHANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-15 US disclosed