Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760502 | 0.83 | DGAT1 (0.37) | LMNADGAT1 | |
| SCHEMBL14690919 | 0.72 | PLG (0.45) | PLGPLATLMNA | |
| SCHEMBL5540803 | 0.66 | PLG (0.52) | PLGPLATLMNA | |
| SCHEMBL6774358 | 0.66 | PLG (0.52) | PLGPLATLMNA | |
| SCHEMBL13668662 | 0.66 | PLG (0.42) | PLGPLATLMNA | |
| SCHEMBL28958600 | 0.66 | PLG (0.42) | PLGPLATLMNA | |
| SCHEMBL352832 | 0.66 | DRD2 (0.49) | — | |
| SCHEMBL3943582 | 0.66 | DRD2 (0.49) | — | |
| SCHEMBL3943109 | 0.66 | ACACB (0.51) | — | |
| SCHEMBL1972715 | 0.66 | NCF1 (0.41) | PLGPLATLMNADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |
| EP-1089967-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067206-A1 | NOVEL COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 1999-12-29 | — | — | WO | disclosed |